The domain within your query sequence starts at position 354 and ends at position 462; the E-value for the 4dex domain shown below is 6e-36.

EFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNSGTSALEVLRR
ATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSTKVDGASYFRHK

This is a PDB domain - please see the PDBSUM entry of 4dex for further annotation